Cholecystokinin from the entorhinal cortex enables neural plasticity in the auditory cortex
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چکیده
منابع مشابه
Neuronal Plasticity in the Entorhinal Cortex
The entorhinal cortex (EC) is a unique and fascinating structure, constituting a highly parallel interface between phylogenetically old cortex (hippocampus) and higher neo-cortical areas. The literature related to the EC has increased dramatically in the past 30 years. A simple PubMed search for EC lists around 20–40 articles per year in the early 1980s. This more than doubled by the beginning ...
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Cholecystokinin Facilitates Neuronal Excitability in the Entorhinal Cortex via Activation 1 of TRPC-like Channels 2 Shouping Wang, An-Ping Zhang, Lalitha Kurada, Toshimitsu Matsui and Saobo Lei 3 From Department of Pharmacology, Physiology and Therapeutics, School of Medicine and 4 Health Sciences, University of North Dakota, Grand Forks, ND58203, USA; Department of 5 Anesthesiology, Sun Yat-se...
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Arguably the most important property of neuronal circuits in general, and of cortical circuits in particular, is plasticity--the ability to change in response to past experience. While many studies of plasticity emphasize changes in excitatory transmission, in this issue of Neuron, Galindo-Leon et al. demonstrate the important role that increased inhibition may play in shaping cortical response...
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1. INTRODUCTION How does the primary auditory cortex (A1) derive its function? Is it primarily determined by intrinsic factors expressed within cortex (i.e. molecular gradients, patterns of gene expression) or extrinsic factors that originate outside cortex (i.e. sensory experience)? This is a pivotal issue for understanding the development and function of A1, yet one that is difficult to addre...
متن کاملPlasticity in the entorhinal cortex suppresses memory for contextual fear.
Several studies have delineated a role for the hippocampus in fear conditioning. However, in this task, the role of the entorhinal cortex (EC), the main input-output structure for the hippocampus, is uncertain. The extracellular signal-regulated kinase (ERK) cascade has been shown to be a molecular correlate for long-term memory, and its activity is required for various types of memory storage,...
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ژورنال
عنوان ژورنال: Cell Research
سال: 2013
ISSN: 1001-0602,1748-7838
DOI: 10.1038/cr.2013.164